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Systems for early detection of clinical deterioration in older people in non-hospital settings – a systematic scoping review


Background: Many older people are vulnerable and extra prone to clinical deterioration. Healthcare personnel therefore need to be extremely skilled in observation. Tools for early detection of clinical deterioration are becoming more common, also in non-hospital settings, but the current evidence base primarily consists of research from hospital populations.

Objective: To find and describe research on tools for early detection of clinical deterioration in older people in non-hospital settings.

Method: In the scoping review, we used the Joanna Briggs Institute’s methodology for scoping reviews, and we published the protocol for the study in the Open Science Framework. A systematic literature search was performed in a relevant selection of databases in May 2021, and this forms the basis for the review. Two people screened all the articles independently according to predefined inclusion and exclusion criteria. We extracted data relating to the research question and summarised and presented these in tables and graphs.

Results: In total, 45 studies are included in the scoping review. In recent years, there has been a marked increase in studies examining the use of tools for early detection of clinical deterioration. A few of these studies have a particular focus on older people, and most deal with the ambulance service. As many as 14 different tools for early detection of clinical deterioration (also known as Early Warning Scores (EWSs)) were identified in the selected studies, the most common of which are MEWS, NEWS and NEWS2. Qualitative studies on the use of such scoring systems may indicate that they are useful as decision support for healthcare personnel who need to assess clinical deterioration in a patient.

Conclusion: This study shows a large increase in the number of studies in recent years on tools for early detection of clinical deterioration in non-hospital settings. The increase may be a reflection of the greater focus on and growing need for such scoring systems in decision support. Nevertheless, there are surprisingly few studies with a particular focus on older people and primary care. This is paradoxical given the weak evidence base of the national clinical guidance that recommends such systems. We recommend use of such systems and prioritisation of the knowledge gap.

Cite the article

Steinseide E, Potrebny T, Ciliska D, Graverholt B. Systems for early detection of clinical deterioration in older people in non-hospital settings – a systematic scoping review. Sykepleien Forskning. 2020; 15(88361):e-88361. DOI: 10.4220/Sykepleienf.2022.88361en

Older patients with underlying health conditions constitute a vulnerable group that is particularly prone to clinical deterioration (1). They often display non-specific symptoms of their condition, and these can stem from a completely different organ system to the one where their acute illness is located (2).

In addition, acute illness in older people is often characterised by loss of function, which can be misinterpreted as a care problem as opposed to a health issue (1). Older people can quickly become acutely ill, and observation skills is needed to identify clinical deterioration at an early stage (2). Lack of such competence can lead to conditions and diseases not being diagnosed, which constitutes a serious risk in terms of patient safety. Acute functional decline in older people can go undetected, and signs of serious illness can, at worst, be overlooked (1).

A high level of observation skills is therefore a particularly important part of patient safety when caring for older people. This is in line with the primary care service’s responsibility for providing services that are safe, and which are preferably founded on evidence-based guidelines (3–5).

Many primary care staff are unskilled, and registered nurses (RNs) often have sole responsibility for patients (6). Being able to observe and critically assess a patient’s condition is a vital skill for RNs (7). They must also know how to react and what to do when a patient’s condition deteriorates (8).

The uncertain situation surrounding clinical observations and assessments is confirmed in the review by Preston and Flynn (8). A review of basic observation skills in primary care in Norway by Bing-Jonsson et al. (9) found that competence among primary care staff varies in relation to observation, basic assessments and measuring vital signs.

We know that one-third of hospital deaths could be prevented as they are associated with a lack of clinical monitoring of patients (10). About half of all patient injuries occur in primary care, where older people constitute the largest patient group (4).

Older patients are a heterogenous group, ranging from people living at home with minor health challenges to frail nursing home residents with comorbidities and functional impairments (11).

In Norway, the National Early Warning Score (NEWS/NEWS2) (Figure 1) and Modified Early Warning Score (MEWS) are perhaps the most well-known and most-used tools for early detection of clinical deterioration. The generic term for such systems is early warning score (EWS).

The EWS system was developed to standardise and quality assure the assessment of and response to clinical deterioration (12). Older patients often have atypical symptoms, and they need to be monitored for changes in vital signs in order to identify clinical deterioration at an early stage (2).

All of these scoring systems are based on observations of vital signs such as systolic blood pressure, pulse rate, respiration rate and temperature, which are then recorded on a standardised clinical chart.

Different scores trigger different responses, which serves as further decision support for healthcare personnel (13). Use of an EWS to support clinical assessments is a recognised method in Norway and internationally, and is recommended in guidelines and clinical guidance (14–16).

Figure 1. Example of EWS system, NEWS2, Norwegian version

Earlier research into the use of the scoring system in non-hospital settings mainly relates to patient outcomes in ambulances. Research on older people in other settings, such as nursing homes, is less common (13, 14, 17, 18). It would be useful to form a picture of which aspects of this topic are illuminated by research and which are not.

Objective of the study

The objective of this scoping review is to identify, present and describe research on tools for early detection of clinical deterioration in older people in non-hospital settings.


The protocol for this scoping review was published on the Open Science Framework platform in August 2020 (19). We conducted the study in line with Joanna Briggs Institute's methodology for scoping reviews (20), which in turn is based on Arksey and O'Malley’s (21) widely used methodological framework.

The methodology is suitable for obtaining a profile of existing research literature on a given topic and identifying any knowledge gaps. Through nine explicit methodological steps, we found and presented an overview of research on the use of tools for early detection of clinical deterioration in older people in non-hospital settings.

Inclusion criteria

We used the Patient Context Concept (PCC) framework to specify the population, context and concept of the scoping review (20). These elements are reflected in the inclusion criteria that form the basis for a systematic literature search.

We included studies where the population (P) was over the age of 65. We also included studies in which this age group was part of a larger population, and here we tried to retrieve the data that related to the over 65s.

Furthermore, we included studies if they were conducted in non-hospital contexts (C), such as nursing homes, home-based nursing care, GP practices and ambulances. Studies that covered both hospital and non-hospital settings were included if they involved measurements of vital signs in the latter setting.

In addition to these, we included qualitative studies in which healthcare personnel were defined as the study population if they worked with older patients in, for example, nursing homes or home-based nursing care.

The concept (C) in this scoping review is tools for early detection of clinical deterioration. We did not delimit the range of systems, but they had to be used for identifying clinical deterioration based on vital signs. We included all types of primary studies regardless of study design.

Literature search

We performed a three-stage iterative literature search (20) between 1 August and 30 October 2020 and an updated search on 27 May 2021. The first of the three stages entailed an initial search in two databases and subsequent analyses of titles and summaries with a view to identifying additional relevant search terms.

We then conducted the main search in the following databases: Medline Ovid, Cinahl Ebsco, Cochrane Library Central, Epistemonikos and Embase Ovid. In line with the PCC scoping review, we prepared a separate search strategy for each database.

We did not delimit the year of publication or language. All searches were quality assured by a university librarian. In addition, we conducted a manual search, where we went through all reference lists of selected studies as well as those of relevant systematic reviews.

Furthermore, we searched for ongoing studies in Prospero, ClinicalTrials.gov, the WHO International Clinical Trials Registry Platform, the EU Clinical Trials Register and the Open Science Framework (OSF). In order to identify relevant literature that was not found in the databases, we also searched Google Scholar and OpenGrey. The full search strategy is presented in Appendix 1 (partly in Norwegian). 

Selecting studies

Two people screened the entire result of the literature search independently (EGS, BG and TP). We initially assessed the title and abstract in relation to the inclusion criteria.

In cases where it was clear that an article met the inclusion criteria, or if it was unclear, we obtained the full text versions, and two people would then assess them for inclusion independently. Disagreements about inclusion were resolved through discussion or by consulting a third person (DC).

Data collection and analysis

We developed a data collection form based on the inclusion criteria and the following variables: reference, country of origin, purpose, study design, study population, clinical population, age of clinical population, EWS system used, and in what situation, any patient outcomes, how validation studies were carried out, and topic of qualitative studies.

The data collection form was piloted on five articles by two people independently. Data from the remainder of the selected studies were then extracted and collected by one person (EGS) and controlled by another (BG or TP).

We used simple descriptive statistical analyses (frequency, proportion and percentage) to describe the selected studies in terms of context, study design and study population. We used a graph to show which EWS system was used and how often.

We described the results of the qualitative studies in a simple content analysis of the themes we identified in the studies.


As this is a scoping review, it does not require approval by an ethics committee or data protection officer.


In total, we identified 15 853 unique references in the literature search. We ended up including 45 articles after 84 articles were read in full text (Figure 2). One of these was a protocol for ongoing studies (22).

Figure 2. Flow chart for inclusion of articles

Many of the selected studies originated from European countries (n = 39), mostly the UK (n = 16). Five of the studies were conducted in Asia and one in North America. A total of 89% of the studies were carried out in 2015 or later.

Furthermore, a large proportion of the selected studies had different quantitative designs (n = 34), all were observational studies and none were experimental. The qualitative studies (n = 6) were based on either focus group interviews or individual interviews. The characteristics of selected studies are presented in Table 1.

Table 1. Characteristics of studies selected

Only a small number of studies exclusively included older people (n = 6) (23–28). Nevertheless, the mean age (and/or median age) was over 65 years in all the studies selected. A few had a median or mean age of over 80 years (n = 4) (26–29). Some studies focused exclusively on sepsis (27, 30–35), but most studies were not limited to a specific diagnosis.

The largest proportion of studies were conducted in the ambulance service (n = 25). A smaller proportion (n = 6) was carried out in nursing homes (23, 25, 26, 28, 36), at GP practices (n = 1) (37) and municipal acute bed units (38), and two were from home-based nursing care (n = 2) (29, 39).

Three of the studies took place across different settings (32, 40, 41). The study populations in the qualitative studies and implementation studies were made up of healthcare personnel.

We identified 14 different EWS systems

We identified a total of 14 different EWS systems, and more than half of the articles related to NEWS or NEWS2 (Figure 3 and Table 2). Only a few of the studies examined the actual use of the systems (n = 5). In most cases, data were collected retrospectively (24, 25, 27, 30, 31, 33-35, 42–62).

We found that early warning scoring was largely based on clinical indication, i.e. when acute illness was suspected. We only identified one validation study, which examined reliability and validity for the Pre-hospital Medical Emergencies Early Warning Scale (Pre-MEWS) (63).

Figure 3. Different systems and use in studies
Table 2. Vital parameters in the different EWS systems

The most common patient outcome in the quantitative studies was mortality (n = 23). Admission to hospital or an ICU (n = 15) and further deterioration and complications (n = 8) were also widely investigated outcomes. A few studies examined whether the use of an EWS affected attendance by a doctor (n = 2) and re-admission (n = 2).

The qualitative studies focused on experiences with EWS as decision support and a communication tool. Topics such as reassurance and support in clinical assessments were reported most often (n = 7). Other topics that were highlighted in qualitative research were implementation, training and challenges relating to the correct use of EWS (29, 32).

In the tables, the selected studies are sorted into quantitative studies ( Appendix 2. Quantitative studies included) (24–28, 30, 31, 33–35, 38, 42–62, 64–66), qualitative studies (Appendix 3. Qualitative studies included) (23, 28, 36, 39–41, 67), implementation and validation studies (Appendix 4. Implementation and validation studies and protocols included) (29, 32, 63), and protocols (22) respectively.

We also produced an overview of articles that we read in full text and then excluded, and state the reason for the exclusion (Appendix 5. Studies excluded, with reason for exclusion).


In this scoping review, we identified and described research-based knowledge on the use of tools for early detection of clinical deterioration in older people in non-hospital settings. We identified 14 different EWS systems, all with small variations. MEWS, NEWS and NEWS2 were the most common.

Research in the field mainly consists of quantitative observational studies as well as some qualitative studies and a few implementation studies. There is a clear trend for more research on EWS systems in recent years, but in relation to older people in non-hospital settings this research is still limited. Few studies have been conducted in nursing homes and in home-based nursing care.

Lack of research on EWS and older people

There is surprisingly little research on the use of EWS in settings where RNs meet vulnerable older people, such as nursing homes and home-based nursing care.

Since 2018, the Norwegian Directorate of Health has recommended using NEWS2 in the primary health and care services, as a component in the patient safety programme (5), and recently the package of measures in the Safe Hands programme (I trygge hender 24/7) was continued in the form of national clinical guidance (15).

This means that national health authorities are making recommendations using a seemingly poor evidence base. Nevertheless, the growing trend for studies reflects the strong focus on generating knowledge about these tools, which in turn may be a sign of increased use and a major need for such systems.

The alternative to such tools is discretionary assessments, a poor decision basis and perhaps imprecise communication about the patient’s condition. Given that the observational competence of healthcare personnel may be inadequate (9), it is probably safer to use such a tool – provided that it is used correctly (14).

In addition, the evidence base for using EWS in the specialist health service is clearer (13, 14, 68, 69), and it may be possible to use this indirectly in non-hospital settings. For example, several studies from the specialist health service found that using EWS has an impact on patient outcomes, including mortality (14, 68, 69).

A discernible knowledge gap persists

This scoping review shows that the evidence base for recommending use of EWS in non-hospital settings is weak. We have identified a discernible knowledge gap that should be prioritised. The need for research has been pointed out in earlier systematic reviews (17, 18), but our review shows that the knowledge gap still remains.

This scoping review shows that the evidence base for recommending use of EWS in non-hospital settings is weak.

In particular, we lack studies with robust prospective designs to assess the effects of using EWS in pre-hospital settings (17, 18), which is a prerequisite for an evidence-based approach (70). Nevertheless, the number of studies conducted in non-hospital settings has generally increased, which may reflect the interest in and need for such tools.

We identified as many as 14 different EWS systems. The question is therefore which of these is best suited for use on older people in non-hospital settings. The national authorities in Norway and the Royal College of Physicians in the UK recommend use of NEWS2 in their guidelines and clinical guidance (12, 15).

The studies do not compare different EWS systems

The selected studies offer little comparison of the various EWS systems. Consequently, they do not provide any enlightenment as to which tool is ‘the best’, and this is also beyond the remit of a scoping overview.

More tools were identified than in earlier systematic reviews (17, 18). Downey and Tahir (14) recommend that only one tool is used in order to create a universal language across the different contexts.

However, it is also important to consider whether the same tools can actually be used on frail older people with complex clinical pictures and comorbidities in non-hospital settings and on young adults in hospitals or in other contexts.

EWS systems have been criticised for their use in settings and for populations other than those for which they were developed (71). This is not covered to any extent in the research literature.

EWS cannot replace clinical assessments by healthcare personnel

The qualitative studies and implementation studies show that healthcare personnel have expressed a need for decision support in situations where EWS is intended to serve as an aid, and for such systems to be useful and relevant. Nevertheless, it appears that EWS can never replace clinical assessments performed by healthcare personnel (23, 28, 36, 39, 67).

One of the objections to EWS is precisely because it can be regarded as a substitute for a comprehensive clinical assessment as opposed to a supporting tool (71). This is confirmed by Jeppestøl and Kirkevold (39), who highlight the importance of knowing the patients when using the instruments.

Healthcare personnel have expressed a need for decision support in situations where EWS is intended to serve as an aid.

RNs are an important resource, and their competence should be used properly and developed where necessary. Observation skills is crucial for assessing health challenges in older people with complex clinical pictures (2), and the need for basic observation skills was identified by Bing-Jonsson et al. (9).

The tools can provide good support, but require correct use and the right skills. It is therefore important not to underestimate the importance of the implementation of such tools (15) as part of a systematic, planned process, in which there should also be a focus on validity over time (72).

The scoping review seems to document a major need for decision support, while the literature shows challenges in relation to competence, training and implementation of EWS systems.


The qualitative studies in this scoping review highlight the benefits of using EWS, and show that it has a particularly positive impact on decision support and communication. However, targeted training is crucial for personnel being able to use the tools properly. This is often the responsibility of the RNs in primary health and care services.

A number of knowledge gaps exist in relation to the use of EWS in nursing homes, in home-based nursing care and for older people in general. One of the areas where there is reason to update and refine systematic reviews is in the ambulance service.

A number of knowledge gaps exist in relation to the use of EWS in nursing homes, in home-based nursing care and for older people in general.

Furthermore, there is a marked need for prospective cohort studies that can evaluate the effect of EWS systems aimed at older patients in nursing homes and home-based nursing care. It would also be useful to know which of the 14 systems is best suited for early detection of clinical deterioration in older people in non-hospital settings.

Strengths and limitations of the methodology

Systematic scoping reviews are intended to identify the research that exists in a specific field, in this case tools for early detection of clinical deterioration in older people in non-hospital settings. The methodology is the greatest strength of this review, namely that it provides an overview of the research that exists in the field.

Nevertheless, it is important to point out that it is beyond the remit of a scoping review to assess the quality of the methodologies in the selected studies, including the risk of systematic biases. This must be taken into account when interpreting and using the results from this scoping review.

One of the strengths of the scoping review is the protocol we published beforehand, which reduces the risk of selection bias in the study. Another strength is the broad and iterative literature search that formed the basis of the data collection, which was also quality assured by a university librarian.

It should nevertheless be noted that there is always a certain risk that some studies will not be picked up in the search. However, the fact that two people selected the studies independently of each other is a strength of the review.

One weakness of the method was that that two people independently extracted data from the articles in only 15 of the 45 studies selected. However, we piloted the process in order to extract data in advance, since we found good conformity when two people went through 15 articles.


This scoping review shows that research activity in tools for early detection of clinical deterioration is experiencing rapid growth both in Norway and internationally. However, this trend is not seen in relation to use in typical primary care settings such as home-based nursing care and nursing homes.

Little is known about the contribution of these tools in such settings, which is a paradox considering that they are recommended in national clinical guidance. Most studies on EWS for older people are from the ambulance service.

The general increase in research on EWS is probably due to several factors, the most important of which is perhaps the real, significant need for standardised tools to aid decision-making in complex assessments.

Future studies on the use of EWS for older people in non-hospital settings should have a more robust, prospective and controlled design in order to generate knowledge on the benefits for the patient group and healthcare personnel in primary care.

The study is part of the IMPAKT project, which is funded by the Research Council of Norway (256569) (73).

The study was conducted for a master’s thesis in the master's degree in evidence-based practice in health sciences at the Western Norway University of Applied Sciences. I would like to thank the university's librarian, Gøril Tvedten Jorem, for her invaluable support in the design and peer review of the literature search.

Fact box
The study’s contribution of new knowledge
  • Tools for early detection of clinical deterioration are increasingly being used as decision support for identifying patients at risk of clinical deterioration, but the evidence base for use with older people in non-hospital settings is weak.
  • This study provides a systematic overview of research on the use of such tools with older people in non-hospital settings.
  • Healthcare personnel are positive about using EWS, but emphasise that it has to be well implemented, with proper training and reflection on the tool as a supplement to, not a substitute for, their own clinical assessments. Several of the knowledge gaps we have identified should be filled to strengthen RNs’ evidence base for using tool with older patient groups in non-hospital settings. This also applies to knowledge about implementing the tools in different contexts.


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